Current progress, challenges, and future perspectives of language models for protein representation and protein design

The sequence-structure-function paradigm of protein is the basis of molecular biology. What is the underlying mechanism of such sequence and structure/function corresponding relationship? We reviewed the methods for protein representation and protein design. With these protein representation models,...

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Bibliographic Details
Main Authors: Tao Huang, Yixue Li
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:The Innovation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666675823000747