SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle

SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle

Abstract MCT1 is a critical protein found in monocarboxylate transporters that plays a significant role in regulating the lactate shuttle. However, the post‐transcriptional modifications that regulate MCT1 are not clearly identified. In this study, it is reported that SETDB1 interacts with MCT1, lea...

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Bibliographic Details
Main Authors: Xiaowei She, Qi Wu, Zejun Rao, Da Song, Changsheng Huang, Shengjie Feng, Anyi Liu, Lang Liu, Kairui Wan, Xun Li, Chengxin Yu, Cheng Qiu, Xuelai Luo, Junbo Hu, Guihua Wang, Feng Xu, Li Sun
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Advanced Science
Subjects:
lactate shuttle
MCT1 methylation
SETDB1
tumor progression
Online Access:https://doi.org/10.1002/advs.202301871

Internet

https://doi.org/10.1002/advs.202301871

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