The Intriguing Connections between von Willebrand Factor, ADAMTS13 and Cancer

von Willebrand factor (VWF) is a complex and large protein that is cleaved by ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13), and together they serve important roles in normal hemostasis. Malignancy can result in both a deficiency or excess of VWF, leading...

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Bibliographic Details
Main Authors: Chanukya K. Colonne, Emmanuel J. Favaloro, Leonardo Pasalic
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/10/3/557