Analytic optimization of Plasmodium falciparum marker gene haplotype recovery from amplicon deep sequencing of complex mixtures.

Analytic optimization of Plasmodium falciparum marker gene haplotype recovery from amplicon deep sequencing of complex mixtures.

Molecular epidemiologic studies of malaria parasites and other pathogens commonly employ amplicon deep sequencing (AmpSeq) of marker genes derived from dried blood spots (DBS) to answer public health questions related to topics such as transmission and drug resistance. As these methods are increasin...

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Bibliographic Details
Main Authors: Zena Lapp, Elizabeth Freedman, Kathie Huang, Christine F Markwalter, Andrew A Obala, Wendy Prudhomme-O'Meara, Steve M Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLOS Global Public Health
Online Access:https://doi.org/10.1371/journal.pgph.0002361

Internet

https://doi.org/10.1371/journal.pgph.0002361

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