Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway

Epilepsy is a neurological disease and approximately 30% of patients have failed to respond to current anti-epilepsy drugs. The neuroinflammation mechanism has raised increasing concerns and been regarded as the novel treatment strategy in epilepsy, but the target molecules require further research....

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Bibliographic Details
Main Authors: Xinlin Li, Rong Zhou, Hui Peng, Jing Peng, Qiaoling Li, Meng Mei
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/13/2/262