Utilizing FMR1 gene mutations as predictors of treatment success in human in vitro fertilization.

Mutations of the fragile X mental retardation 1 (FMR1) gene are associated with distinct ovarian aging patterns.To confirm in human in vitro fertilization (IVF) that FMR1 affects outcomes, and to determine whether this reflects differences in ovarian aging between FMR1 mutations, egg/embryo quality...

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Main Authors: Vitaly A Kushnir, Yao Yu, David H Barad, Andrea Weghofer, Eric Himaya, Ho-Joon Lee, Yan-Guang Wu, Aya Shohat-Tal, Emanuela Lazzaroni-Tealdi, Norbert Gleicher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4096763?pdf=render