MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection

MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection

Abstract Background MicroRNAs (miRNAs) are involved in the regulation of both the innate and adaptive immune response to Cryptosporidium parvum infection. We previously reported that C. parvum upregulated miR‑942‑5p expression in HCT‑8 cells via TLR2/TLR4‑NF‑κB signaling. In the present study, the r...

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Bibliographic Details
Main Authors: Fujie Xie, Yajun Zhang, Juanfeng Li, Lulu Sun, Longxian Zhang, Meng Qi, Sumei Zhang, Fuchun Jian, Xiaoying Li, Junqiang Li, Changsheng Ning, Rongjun Wang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Parasites & Vectors
Subjects:
Cryptosporidium parvum
HCT-8 cell
miR-942-5p
Apoptosis
Parasite burden
Online Access:https://doi.org/10.1186/s13071-022-05415-3

Internet

https://doi.org/10.1186/s13071-022-05415-3

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