De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways
Despite the advent of tyrosine kinase inhibitors, a proportion of chronic myeloid leukemia patients in chronic phase fail to respond to imatinib or to second-generation inhibitors and progress to blast crisis. Until now, improvements in the understanding of the molecular mechanisms responsible for c...
প্রধান লেখক: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Ferrata Storti Foundation
2019-09-01
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মালা: | Haematologica |
অনলাইন ব্যবহার করুন: | https://haematologica.org/article/view/9045 |