Proteomic analysis of ascitic extracellular vesicles describes tumour microenvironment and predicts patient survival in ovarian cancer

Proteomic analysis of ascitic extracellular vesicles describes tumour microenvironment and predicts patient survival in ovarian cancer

Abstract High‐grade serous carcinoma of the ovary, fallopian tube and peritoneum (HGSC), the most common type of ovarian cancer, ranks among the deadliest malignancies. Many HGSC patients have excess fluid in the peritoneum called ascites. Ascites is a tumour microenvironment (TME) containing variou...

Full description

Bibliographic Details
Main Authors: Anna Vyhlídalová Kotrbová, Kristína Gömöryová, Antónia Mikulová, Hana Plešingerová, Stanislava Sladeček, Marek Kravec, Šárka Hrachovinová, David Potěšil, Garett Dunsmore, Camille Blériot, Mathilde Bied, Jan Kotouček, Markéta Bednaříková, Jitka Hausnerová, Luboš Minář, Igor Crha, Michal Felsinger, Zbyněk Zdráhal, Florent Ginhoux, Vít Weinberger, Vitězslav Bryja, Vendula Pospíchalová
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Journal of Extracellular Vesicles
Subjects:
ascites
extracellular vesicles (EV)
fallopian tube and peritoneum (HGSC)
high‐grade serous carcinoma of the ovary
macrophage
ovarian cancer (OC)
Online Access:https://doi.org/10.1002/jev2.12420

Internet

https://doi.org/10.1002/jev2.12420

Similar Items