Mobile Compensatory Mutations Promote Plasmid Survival

Mobile Compensatory Mutations Promote Plasmid Survival

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ABSTRACT The global dissemination of plasmids encoding antibiotic resistance represents an urgent issue for human health and society. While the fitness costs for host cells associated with plasmid acquisition are expected to limit plasmid dissemination in the absence of positive selection of plasmid...

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Bibliographic Details
Main Authors: Martin Zwanzig, Ellie Harrison, Michael A. Brockhurst, James P. J. Hall, Thomas U. Berendonk, Uta Berger
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSystems
Subjects:
compensatory evolution
chromosomal mutation
plasmid mutation
plasmid persistence
fitness costs
cost compensation
Online Access:https://journals.asm.org/doi/10.1128/msystems.00186-18

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https://journals.asm.org/doi/10.1128/msystems.00186-18

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