Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer

Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer

Abstract Background We investigated the inhibitory effect of pantoprazole on signal transducer and activator of transcription 3 (STAT3) activity and invasiveness of gastric adenocarcinoma cells, and the role of SH2-containing protein tyrosine phosphatase 1 (SHP-1) in mediating role. Methods We used...

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Bibliographic Details
Main Authors: Jin Sung Koh, Moon Kyung Joo, Jong-Jae Park, Hyo Soon Yoo, Byung Il Choi, Beom Jae Lee, Hoon Jai Chun, Sang Woo Lee
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cell & Bioscience
Subjects:
Pantoprazole
Gastric cancer
SH2-containing protein tyrosine phosphatase 1
Signal transducer and activator of transcription 3
Online Access:http://link.springer.com/article/10.1186/s13578-018-0248-9

Internet

http://link.springer.com/article/10.1186/s13578-018-0248-9

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