Metformin: From diabetes to cancer to prolongation of life

The metformin molecule dates back to over a century, but its clinical use started in the ‘50s. Since then, its use in diabetics has grown constantly, with over 150 million users today. The therapeutic profile also expanded, with improved understanding of novel mechanisms. Metformin has a major activ...

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Bibliographic Details
Main Authors: Cesare R. Sirtori, Sofia Castiglione, Chiara Pavanello
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824003128