Rich dynamics and functional organization on topographically designed neuronal networks in vitro

Summary: Neuronal cultures are a prominent experimental tool to understand complex functional organization in neuronal assemblies. However, neurons grown on flat surfaces exhibit a strongly coherent bursting behavior with limited functionality. To approach the functional richness of naturally formed...

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Bibliographic Details
Main Authors: Marc Montalà-Flaquer, Clara F. López-León, Daniel Tornero, Akke Mats Houben, Tanguy Fardet, Pascal Monceau, Samuel Bottani, Jordi Soriano
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222019526