Regulation of hypoxia-inducible factor 1α and induction of vascular endothelial growth factor in a rat neonatal stroke model

Stroke is a devastating condition occurring in at least 1 in 4000 live births in the neonatal period. Since hypoxia-inducible factor (HIF)-1α can modulate ischemic injury via induction of target genes that may protect cells against ischemia, and is induced after preconditioning by hypoxia in the neo...

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Bibliographic Details
Main Authors: Dezhi Mu, Xiangning Jiang, R.Ann Sheldon, Christine K Fox, Shannon E.G Hamrick, Zinaida S Vexler, Donna M Ferriero
Format: Article
Language:English
Published: Elsevier 2003-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001694