The adoptr Package: Adaptive Optimal Designs for Clinical Trials in R

Even though adaptive two-stage designs with unblinded interim analyses are becoming increasingly popular in clinical trial designs, there is a lack of statistical software to make their application more straightforward. The package adoptr fills this gap for the common case of two-stage one- or two-a...

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Bibliographic Details
Main Authors: Kevin Kunzmann, Maximilian Pilz, Carolin Herrmann, Geraldine Rauch, Meinhard Kieser
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2021-06-01
Series:Journal of Statistical Software
Subjects:
Online Access:https://www.jstatsoft.org/index.php/jss/article/view/3844