Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: a causal inference analysis

Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: a causal inference analysis

Abstract Background One of five global deaths are attributable to sepsis. Hyperferritinemic sepsis (> 500 ng/mL) is associated with increased mortality in single-center studies. Our pediatric research network’s objective was to obtain rationale for designing anti-inflammatory clinical trials targ...

Full description

Bibliographic Details
Main Authors: Zhenziang Fan, Kate F. Kernan, Yidi Qin, Scott Canna, Robert A. Berg, David Wessel, Murray M. Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C. Lin, Allan Doctor, Tom Shanley, Tim Cornell, Rick E. Harrison, Athena F. Zuppa, Katherine Sward, J. Michael Dean, H. J. Park, Joseph A. Carcillo
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Critical Care
Subjects:
Severe sepsis
Multiple organ failure
Immunoparalysis
Thrombocytopenia-associated multiple organ failure
Macrophage activation syndrome
Hyperferritinemic sepsis
Online Access:https://doi.org/10.1186/s13054-023-04628-x

Internet

https://doi.org/10.1186/s13054-023-04628-x

Similar Items