The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients

The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients

Abstract Telomere fusions (TFs) can trigger the accumulation of oncogenic alterations leading to malignant transformation and drug resistance. Despite their relevance in tumour evolution, our understanding of the patterns and consequences of TFs in human cancers remains limited. Here, we characteriz...

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Bibliographic Details
Main Authors: Francesc Muyas, Manuel José Gómez Rodriguez, Rita Cascão, Angela Afonso, Carolin M. Sauer, Claudia C. Faria, Isidro Cortés-Ciriano, Ignacio Flores
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44287-8

Internet

https://doi.org/10.1038/s41467-023-44287-8

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