Efficacy and safety of 5-hydroxytryptamine 3 receptor antagonists in irritable bowel syndrome: A systematic review and meta-analysis of randomized controlled trials.

AIM:We assessed the efficacy and safety of 5-hydroxytryptamine (5-HT3) receptor antagonists in adults with non-constipated irritable bowel syndrome (IBS) or diarrhea-predominant IBS (IBS-D). METHODS:We searched PubMed, MEDLINE, EMBASE, and the Cochrane Controlled Trials Register for randomized contr...

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Bibliographic Details
Main Authors: Yongping Zheng, Ting Yu, Yurong Tang, Wenjie Xiong, Xiaoxue Shen, Ling Jiang, Lin Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5349445?pdf=render