Interleukin-1β Promotes Epithelial-Derived Alveolar Elastogenesis via αvβ6 Integrin-Dependent TGF-β Activation

Background/Aims: IL-1β creates persistent pulmonary inflammation accompanied by elevated transforming growth factor β (TGF-β levels and is associated with abnormal elastogenesis, which is observed in bronchopulmonary dysplasia (BPD). Although progress has been made in this field, the mechanisms unde...

Полное описание

Библиографические подробности
Главные авторы: Jiarong Wang, Lei Bao, Benli Yu, Zhaoyun Liu, Wenli Han, Chun Deng, Chunbao Guo
Формат: Статья
Язык:English
Опубликовано: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Серии:Cellular Physiology and Biochemistry
Предметы:
Online-ссылка:http://www.karger.com/Article/FullText/430185