Spatial–temporal order–disorder transition in angiogenic NOTCH signaling controls cell fate specification

Spatial–temporal order–disorder transition in angiogenic NOTCH signaling controls cell fate specification

Angiogenesis is a morphogenic process resulting in the formation of new blood vessels from pre-existing ones, usually in hypoxic micro-environments. The initial steps of angiogenesis depend on robust differentiation of oligopotent endothelial cells into the Tip and Stalk phenotypic cell fates, contr...

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Bibliographic Details
Main Authors: Tae-Yun Kang, Federico Bocci, Qing Nie, José N Onuchic, Andre Levchenko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
angiogenesis
NOTCH signaling
order–disorder transition
Tip–Stalk fate
Turing pattern
Online Access:https://elifesciences.org/articles/89262

Internet

https://elifesciences.org/articles/89262

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