Oxidized Substrates of APEH as a Tool to Study the Endoprotease Activity of the Enzyme

Oxidized Substrates of APEH as a Tool to Study the Endoprotease Activity of the Enzyme

APEH is a ubiquitous and cytosolic serine protease belonging to the prolyl oligopeptidase (POP) family, playing a critical role in the processes of degradation of proteins through both exo- and endopeptidase events. Endopeptidase activity has been associated with protein oxidation; however, the actu...

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Bibliographic Details
Main Authors: Annamaria Sandomenico, Marta Gogliettino, Emanuela Iaccarino, Carmela Fusco, Andrea Caporale, Menotti Ruvo, Gianna Palmieri, Ennio Cocca
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
APEH
oxidized methionine
oxidized substrates
endoproteolytic activity
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/23/1/443

Internet

https://www.mdpi.com/1422-0067/23/1/443

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