Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates

Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates

Abstract Background RNA velocity analysis of single cells offers the potential to predict temporal dynamics from gene expression. In many systems, RNA velocity has been observed to produce a vector field that qualitatively reflects known features of the system. However, the limitations of RNA veloci...

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Bibliographic Details
Main Authors: Shijie C. Zheng, Genevieve Stein-O’Brien, Leandros Boukas, Loyal A. Goff, Kasper D. Hansen
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Genome Biology
Subjects:
Single-cell RNA sequencing
RNA velocity
Online Access:https://doi.org/10.1186/s13059-023-03065-x

Internet

https://doi.org/10.1186/s13059-023-03065-x

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