Evaluation of Temozolomide Treatment for Glioblastoma Using Amide Proton Transfer Imaging and Diffusion MRI

Evaluation of Temozolomide Treatment for Glioblastoma Using Amide Proton Transfer Imaging and Diffusion MRI

This study aimed to evaluate tumor changes due to chemotherapy with temozolomide (TMZ) in terms of quantitative values measured by APT imaging and NODDI. We performed TMZ treatment (administered orally by gavage to the TMZ-40 mg and TMZ-60 mg groups) on 7-week-old male Wistar rats with rat glioma C6...

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Bibliographic Details
Main Authors: Ryutarou Onishi, Reika Sawaya, Keiho Tsuji, Narumi Arihara, Akiko Ohki, Junpei Ueda, Junichi Hata, Shigeyoshi Saito
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
glioblastoma
chemotherapy with temozolomide
7T-MRI
amide proton transfer imaging
neurite orientation dispersion and density imaging
Online Access:https://www.mdpi.com/2072-6694/14/8/1907

Internet

https://www.mdpi.com/2072-6694/14/8/1907

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