Transchromosomic bovine-derived anti-SARS-CoV-2 polyclonal human antibodies protects hACE2 transgenic hamsters against multiple variants

Transchromosomic bovine-derived anti-SARS-CoV-2 polyclonal human antibodies protects hACE2 transgenic hamsters against multiple variants

Summary: Pandemic SARS-CoV-2 has undergone rapid evolution resulting in the emergence of many variants with mutations in the spike protein, some of which appear to evade antibody neutralization, transmit more efficiently, and/or exhibit altered virulence. This raises significant concerns regarding t...

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Bibliographic Details
Main Authors: Theron Gilliland, Matthew Dunn, Yanan Liu, Maria D.H. Alcorn, Yutaka Terada, Shauna Vasilatos, Jeneveve Lundy, Rong Li, Sham Nambulli, Deanna Larson, Paul Duprex, Hua Wu, Thomas Luke, Christoph Bausch, Kristi Egland, Eddie Sullivan, Zhongde Wang, William B. Klimstra
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Immunology
Immune response
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018412

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223018412

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