Screening and Identification of an H-2Kb-Restricted CTL Epitope within the Glycoprotein of Hantaan Virus

Screening and Identification of an H-2Kb-Restricted CTL Epitope within the Glycoprotein of Hantaan Virus

The cytotoxic T lymphocyte (CTL) response plays a key role in controlling viral infection, but only a few epitopes within the HTNV glycoprotein (GP) that are recognized by CTLs have been reported. In this study, we identified one murine HTNV GP-derived H2-Kb-restricted CTL epitope in C57BL/6 mice, w...

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Bibliographic Details
Main Authors: Rui-xue Ma, Lin-Feng Cheng, Qi-kang Ying, Rong-rong Liu, Tie-jun Ma, Xiao-xiao Zhang, Zi-yu Liu, Liang Zhang, Wei Ye, Fang-lin Zhang, Zhi-kai Xu, Fang Wang, Xing-an Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Infection
glycoprotein
IFN-γ
epitope
HTNV
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00151/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00151/full

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