Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis

Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis

Aging is a critical risk factor in idiopathic pulmonary fibrosis (IPF). Dysfunction and loss of type 2 alveolar epithelial cells (AEC2s) with failed regeneration is a seminal causal event in the pathogenesis of IPF, although the precise mechanisms for their regenerative failure and demise remain unc...

Full description

Bibliographic Details
Main Authors: Jiurong Liang, Guanling Huang, Xue Liu, Ningshan Liu, Forough Taghavifar, Kristy Dai, Changfu Yao, Nan Deng, Yizhou Wang, Peter Chen, Cory Hogaboam, Barry R Stripp, William C Parks, Paul W Noble, Dianhua Jiang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
lung injury
aging
alveolar progenoitor
idiopathic pulmonary fibrosis
Online Access:https://elifesciences.org/articles/85415

Internet

https://elifesciences.org/articles/85415

Similar Items