Atorvastatin blocks Sonic Hedgehog medulloblastoma progression through apoptosis

Aberrant activation of Sonic Hedgehog signaling transduction leads to formation of numerous malignancies, including medulloblastoma (MB) – the most common malignant pediatric tumor. Earlier, we have shown that endogenous cholesterol acts as a direct activator of the Sonic Hedgehog signaling and is...

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Bibliographic Details
Main Authors: R.E. Gordon, Z.I. Abramova
Format: Article
Language:English
Published: Kazan Federal University 2017-12-01
Series:Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki
Subjects:
Online Access:https://kpfu.ru/atorvastatin-blocks-sonic-hedgehog_329220.html