Butyrylcholinesterase inhibitory activity of peptides identified from yellow field pea (Pisum sativum) enzymatic protein hydrolysates

Butyrylcholinesterase (BuChE) is an enzyme implicated in Alzheimer’s disease due to the excessive breakdown of neurotransmitters. The study screened and synthesized de novo peptides derived from yellow field pea as BuChE activity inhibitors. The conformational changes of the enzyme were evaluated to...

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Bibliographic Details
Main Authors: Nancy D. Asen, Ogadimma D. Okagu, Chibuike C. Udenigwe, Rotimi E. Aluko
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623001901