FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response

FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response

The intestinal epithelial repair after injury is coordinated by intestinal stem cells (ISCs). Fucosylation catalyzed by fucosyltransferase 2 (FUT2) of the intestinal epithelium is beneficial to mucosal healing but poorly defined is the influence on ISCs. The dextran sulfate sodium (DSS) and lipopoly...

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Bibliographic Details
Main Authors: Zhe Wang, Chen Tan, Caihan Duan, Junhao Wu, Dan Zhou, Lingzhi Hou, Wei Qian, Chaoqun Han, Xiaohua Hou
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Redox Biology
Subjects:
FUT2
Fucosylation
Intestinal stem cell
Inflammatory injury
Apoptotsis
Unfolded protein response
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723000198

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http://www.sciencedirect.com/science/article/pii/S2213231723000198

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