Ecological effects of stress drive bacterial evolvability under sub-inhibitory antibiotic treatments
Abstract Stress is thought to increase mutation rate and thus to accelerate evolution. In the context of antibiotic resistance, sub-inhibitory treatments could then lead to enhanced evolvability, thereby fuelling the adaptation of pathogens. Combining wet-lab experiments, stochastic simulations and...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Oxford University Press
2022-09-01
|
Series: | ISME Communications |
Online Access: | https://doi.org/10.1038/s43705-022-00157-w |