Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice

Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice

Summary: Individuals with fragile X syndrome (FXS) are frequently diagnosed with autism spectrum disorder (ASD), including increased risk for restricted and repetitive behaviors (RRBs). Consistent with observations in humans, FXS model mice display distinct RRBs and hyperactivity that are consistent...

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Bibliographic Details
Main Authors: Francesco Longo, Sameer Aryal, Paul G. Anastasiades, Marta Maltese, Corey Baimel, Federica Albanese, Joanna Tabor, Jeffrey D. Zhu, Mauricio M. Oliveira, Denise Gastaldo, Claudia Bagni, Emanuela Santini, Nicolas X. Tritsch, Adam G. Carter, Eric Klann
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723009129

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http://www.sciencedirect.com/science/article/pii/S2211124723009129

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