Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA

Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA

Thrombosis is a hallmark of the fatal fungal infection mucormycosis. Yet, the platelet activation pathway in response to mucormycetes is unknown. In this study we determined the platelet aggregation potential of Mucor circinelloides (M. circinelloides) NRRL3631, characterized the signaling pathway f...

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Bibliographic Details
Main Authors: Harlene Ghuman, Alicia Shepherd-Roberts, Stephanie Watson, Malou Zuidscherwoude, Steve P. Watson, Kerstin Voelz
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:Platelets
Subjects:
fcγriia
mucor circinelloides
mucormycetes
mucormycosis
platelets
thrombosis
Online Access:http://dx.doi.org/10.1080/09537104.2017.1420152

Internet

http://dx.doi.org/10.1080/09537104.2017.1420152

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