Comprehensive Analysis of the Genetic and Epigenetic Mechanisms of Osteoporosis and Bone Mineral Density

Comprehensive Analysis of the Genetic and Epigenetic Mechanisms of Osteoporosis and Bone Mineral Density

Osteoporosis is a skeletal disorder characterized by a systemic impairment of bone mineral density (BMD). Genome-wide association studies (GWAS) have identified hundreds of susceptibility loci for osteoporosis and BMD. However, the vast majority of susceptibility loci are located in non-coding regio...

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Bibliographic Details
Main Authors:	Hui Dong, Wenyang Zhou, Pingping Wang, Enjun Zuo, Xiaoxia Ying, Songling Chai, Tao Fei, Laidi Jin, Chen Chen, Guowu Ma, Huiying Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-03-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	genome-wide association study osteoporosis bone mineral density summary data-based Mendelian randomization functional element enrichment analysis
Online Access:	https://www.frontiersin.org/article/10.3389/fcell.2020.00194/full

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