MR Imaging and Electrophysiological Features of Doxorubicin-Induced Fibrosis: Protocol Development in a Small Preclinical Pig Study with Histological Validation
A critical chemotherapeutic complication is cardiotoxicity, often leading, in time, to heart failure. In this work, we developed a novel animal protocol using magnetic resonance (MR) imaging and electrophysiology (EP) tests, designed to detect subtle structural and functional changes associated with...
Main Authors: | Peter Lin, Terenz Escartin, Melissa Larsen, Matthew Ng, Mengyuan Li, Jennifer Barry, Idan Roifman, Mihaela Pop |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Applied Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3417/12/22/11620 |
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