Transcriptional adaptation in Caenorhabditis elegans

Transcriptional adaptation is a recently described phenomenon by which a mutation in one gene leads to the transcriptional modulation of related genes, termed adapting genes. At the molecular level, it has been proposed that the mutant mRNA, rather than the loss of protein function, activates this r...

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Bibliographic Details
Main Authors: Vahan Serobyan, Zacharias Kontarakis, Mohamed A El-Brolosy, Jordan M Welker, Oleg Tolstenkov, Amr M Saadeldein, Nicholas Retzer, Alexander Gottschalk, Ann M Wehman, Didier YR Stainier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/50014