Down-regulation of autophagy proteins is associated with higher mTOR expression in the placenta of pregnant women with preeclampsia

Down-regulation of autophagy proteins is associated with higher mTOR expression in the placenta of pregnant women with preeclampsia

Autophagy is a lysosomal degradation pathway that removes protein aggregates and damaged organelles maintaining cellular integrity. It seems to be essential for cell survival during stress, starvation, hypoxia, and consequently to the placenta implantation and development. Preeclampsia (PE) is a mul...

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Bibliographic Details
Main Authors: I.C. Weel, V.R. Ribeiro, M. Romão-Veiga, E.G. Fioratti, J.C. Peraçoli, M.T.S. Peraçoli
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2023-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Autophagy
LC3
Beclin-1
mTOR
Placenta
Preeclampsia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100683&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100683&tlng=en

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