Modular Synthesis and Antiproliferative Activity of New Dihydro-1<i>H</i>-pyrazolo[1,3-<i>b</i>]pyridine Embelin Derivatives

Modular Synthesis and Antiproliferative Activity of New Dihydro-1<i>H</i>-pyrazolo[1,3-<i>b</i>]pyridine Embelin Derivatives

A set of new dihydro-1<i>H</i>-pyrazolo[1,3-<i>b</i>]pyridine and pyrazolo[1,3-<i>b</i>]pyridine embelin derivatives was synthesized through a multicomponent reaction from natural embelin, 3-substituted-5-aminopyrazoles and aldehydes. The synthesized compounds wer...

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Bibliographic Details
Main Authors: Pedro Martín-Acosta, Ángel Amesty, Miguel Guerra-Rodríguez, Borja Guerra, Leandro Fernández-Pérez, Ana Estévez-Braun
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceuticals
Subjects:
multicomponent reaction
embelin
antiproliferative activity
SAR
Online Access:https://www.mdpi.com/1424-8247/14/10/1026

Internet

https://www.mdpi.com/1424-8247/14/10/1026

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