Accumulation of plasmacytoid dendritic cell is associated with a treatment response to DNA-damaging treatment and favorable prognosis in lung adenocarcinoma

Accumulation of plasmacytoid dendritic cell is associated with a treatment response to DNA-damaging treatment and favorable prognosis in lung adenocarcinoma

IntroductionFavorable responses to the treatment including immune checkpoint inhibitors (ICIs) have been consistently reported in lung cancer with smoking history. As the tumor microenvironment (TME) may be involved in the treatment response to ICIs, we aimed to investigate the TME of lung cancer wi...

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Bibliographic Details
Main Authors: Yoon Jin Cha, Eun Young Kim, Yong Jun Choi, Chi Young Kim, Min Kyung Park, Yoon Soo Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint inhibitors (ICIs)
lung adenocarcinoma
plasmacytoid dendritic cells (pDCs)
single cell RNA sequencing(scRNA-seq)
smoking
toll-like receptor 9 (TLR9)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1154881/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1154881/full

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