Mitochondrial Trafficking and Processing of Telomerase RNA TERC
Summary: Mitochondrial dysfunctions play major roles in many diseases. However, how mitochondrial stresses are relayed to downstream responses remains unclear. Here we show that the RNA component of mammalian telomerase TERC is imported into mitochondria, processed to a shorter form TERC-53, and the...
Main Authors: | Ying Cheng, Peipei Liu, Qian Zheng, Ge Gao, Jiapei Yuan, Pengfeng Wang, Jinliang Huang, Leiming Xie, Xinping Lu, Tanjun Tong, Jun Chen, Zhi Lu, Jisong Guan, Geng Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718312440 |
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