DEVELOPMENT AND VALIDATION OF THE METHOD OF KINETIC EVALUATION OF MEDICAL SUBSTANCE TOPIRAMAT DISSOLUTION BY LASER DIFFRACTION OF LIGHT METHOD

Solubility is the most important quality indicator, reflecting the physicochemical properties of active pharmaceutical ingredients (APIs). Prior to the release of API, solubility is one of the key factors affecting the efficacy and safety of drugs. Therefore, the directed development of new drugs wi...

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Bibliographic Details
Main Authors: E. V. Uspenskaya, A. A. Keshishian, M. V. Nikiforova, T. V. Pletneva, A. V. Syroeshkin
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/580