Role of Cytokine Combinations on CD4+ T Cell Differentiation, Partial Polarization, and Plasticity: Continuous Network Modeling Approach

Role of Cytokine Combinations on CD4+ T Cell Differentiation, Partial Polarization, and Plasticity: Continuous Network Modeling Approach

Purpose: We put forward a theoretical and dynamical approach for the semi-quantitative analysis of CD4+ T cell differentiation, the process by which cells with different functions are derived from activated CD4+ T naïve lymphocytes in the presence of particular cytokine microenvironments. We explore...

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Bibliographic Details
Main Authors: Mariana E. Martinez-Sanchez, Leonor Huerta, Elena R. Alvarez-Buylla, Carlos Villarreal Luján
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
CD4+ T cells
regulatory network
ODE
heterogeneity
plasticity
micro-environment
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00877/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00877/full

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