LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion

LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion

The low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor mediating the clearance of various molecules from the extracellular matrix. LRP1 also regulates cell surface expression of matrix receptors by modulating both extracellular and intracellular signals...

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Bibliographic Details
Main Authors: Benoit Langlois, Julie Martin, Christophe Schneider, Cathy Hachet, Christine Terryn, Damien Rioult, Laurent Martiny, Louis Théret, Stéphanie Salesse, Stéphane Dedieu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
LRP-1
cancer
adhesion receptors
cell-matrix interactions
invasive potential
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.981927/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.981927/full

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