Fluconazole-Induced Ploidy Change in <named-content content-type="genus-species">Cryptococcus neoformans</named-content> Results from the Uncoupling of Cell Growth and Nuclear Division

Fluconazole-Induced Ploidy Change in <named-content content-type="genus-species">Cryptococcus neoformans</named-content> Results from the Uncoupling of Cell Growth and Nuclear Division

ABSTRACT Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies linked azole resistance to elevated numbers of cop...

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Bibliographic Details
Main Authors: Sophie Altamirano, Diana Fang, Charles Simmons, Shreyas Sridhar, Peipei Wu, Kaustuv Sanyal, Lukasz Kozubowski
Format: Article
Language:English
Published: American Society for Microbiology 2017-06-01
Series:mSphere
Subjects:
antifungal resistance
cytokinesis
heteroresistance
ploidy
yeasts
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00205-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00205-17

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