Effects of testosterone and 17β-estradiol on osteogenic and adipogenic differentiation capacity of human bone-derived mesenchymal stromal cells of postmenopausal women

Progressive bone loss is a predominant symptom of aging and osteoporosis. Therefore, the effects of sex steroids (i.e. testosterone and 17β-estradiol) on the differentiation capacity of human bone-derived mesenchymal stromal cells (hMSCs), as progenitors of osteoblasts and adipocytes, are of particu...

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Bibliographic Details
Main Authors: Kristina Glenske, Gerhard Schuler, Stefan Arnhold, Mohamed I. Elashry, Alena-Svenja Wagner, Mike Barbeck, Elena Neumann, Ulf Müller-Ladner, Reinhard Schnettler, Sabine Wenisch
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Bone Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187219300324