Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence

Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence

<p>Abstract</p> <p>Background</p> <p>Defensins are important components of innate immunity to combat bacterial and viral infections, and can even elicit antitumor responses. Clusters of defensin (DEF) genes are located in a 2 Mb range of the human chromosome 8p23.1. Thi...

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Main Authors: Loncarevic Ivan F, Frankish Adam, Asakawa Shuichi, Shimizu Atsushi, Szafranski Karol, Schilhabel Markus, Reichwald Kathrin, Huse Klaus, Galgoczy Petra, Taudien Stefan, Shimizu Nobuyoshi, Siddiqui Roman, Platzer Matthias
Format: Article
Language:English
Published: BMC 2004-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/5/92

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http://www.biomedcentral.com/1471-2164/5/92

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