Constitutive β-catenin signaling by the viral chemokine receptor US28.

Constitutive β-catenin signaling by the viral chemokine receptor US28.

Chronic activation of Wnt/β-catenin signaling is found in a variety of human malignancies including melanoma, colorectal and hepatocellular carcinomas. Interestingly, expression of the HCMV-encoded chemokine receptor US28 in intestinal epithelial cells promotes intestinal neoplasia in transgenic mic...

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Bibliographic Details
Main Authors: Ellen V Langemeijer, Erik Slinger, Sabrina de Munnik, Andreas Schreiber, David Maussang, Henry Vischer, Folkert Verkaar, Rob Leurs, Marco Siderius, Martine J Smit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23145028/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23145028/?tool=EBI

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