Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region

Abstract Background Overweight and obesity are defined by an anomalous or excessive fat accumulation that may compromise health. To find single-nucleotide polymorphisms (SNPs) influencing metabolic phenotypes associated with the obesity state, we analyze multiple anthropometric and clinical paramete...

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Main Authors: Lara P. Fernández, Nerea Deleyto-Seldas, Gonzalo Colmenarejo, Alba Sanz, Sonia Wagner, Ana Belén Plata-Gómez, Mónica Gómez-Patiño, Susana Molina, Isabel Espinosa-Salinas, Elena Aguilar-Aguilar, Sagrario Ortega, Osvaldo Graña-Castro, Viviana Loria-Kohen, Pablo J. Fernández-Marcos, Alejo Efeyan, Ana Ramírez de Molina
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Genome Biology
Subjects:
Obesity
Overweight
Metabolism
mTOR
FNIP2
Folliculin complex
Online Access:https://doi.org/10.1186/s13059-022-02798-5

Internet

https://doi.org/10.1186/s13059-022-02798-5

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