Rad51 and Rad52 are involved in homologous recombination of replicating herpes simplex virus DNA.

Replication of herpes simplex virus 1 is coupled to recombination, but the molecular mechanisms underlying this process are poorly characterized. The role of Rad51 and Rad52 recombinases in viral recombination was examined in human fibroblast cells 1BR.3.N (wild type) and in GM16097 with replication...

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Bibliographic Details
Main Authors: Ka-Wei Tang, Peter Norberg, Martin Holmudden, Per Elias, Jan-Åke Liljeqvist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4218770?pdf=render