Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach

Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach

Acetylcholinesterase (AChE) enzymes play an essential role in the development of Alzheimer’s disease (AD). Its excessive activity causes several neuronal problems, particularly psychopathies and neuronal cell death. A bioactive pose on the <i>h</i>AChE B site of the human acetylcholinest...

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Bibliographic Details
Main Authors: Luciane B. Silva, Elenilze F. B. Ferreira, Maryam, José M. Espejo-Román, Glauber V. Costa, Josiane V. Cruz, Njogu M. Kimani, Josivan S. Costa, José A. H. M. Bittencourt, Jorddy N. Cruz, Joaquín M. Campos, Cleydson B. R. Santos
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Alzheimer’s disease
ADME
molecular docking and molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/28/3/1035

Internet

https://www.mdpi.com/1420-3049/28/3/1035

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