Current HDAC Inhibitors in Clinical Trials

Epigenetic modifications in eukaryotic biological pathways can lead to the up- or downregulation of regulatory proteins contributing to disease onset and progression. In the last three decades, histone deacetylases (HDACs) are among the most studied epigenetic targets. In fact, aberrant HDAC expres...

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Bibliographic Details
Main Authors: Elisabetta Di Bello, Beatrice Noce, Rossella Fioravanti, Antonello Mai
Format: Article
Language:deu
Published: Swiss Chemical Society 2022-05-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/6040